| Identification | Back Directory | [Name]
H-SER-LEU-ILE-GLY-ARG-LEU-OH | [CAS]
164081-25-8 | [Synonyms]
SLIGRL
SER-LEU-ILE-GLY-ARG-LEU
PAR-2 (1-6) (MOUSE, RAT)
H-SER-LEU-ILE-GLY-ARG-LEU-OH
PAR-2 AGONIST PEPTIDE (SLIGRL), MOUSE
H-SER-LEU-ILE-GLY-ARG-LEU-OH USP/EP/BP
L-Seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucine
L-Leucine, L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-
PROTEINASE ACTIVATED RECEPTOR 2 AGONIST PEPTIDE (SLIGRL), MOUSE
PAR-2 (1-6) (mouse, rat) trifluoroacetate salt H-Ser-Leu-Ile-Gly-Arg-Leu-OH trifluoroacetate salt
Coagulation Factor II Receptor-Like 1 (1-6) (Mouse, rat), Proteinase Activated Receptor 2 (1-6) (Mouse, rat), SLIGRL, ThroMbin Receptor-Like 1 (1-6) (Mouse, rat)
(2S)-2-[[(2S)-2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoic acid | [Molecular Formula]
C29H55N9O8 | [MDL Number]
MFCD00467908 | [MOL File]
164081-25-8.mol | [Molecular Weight]
657.8 |
| Chemical Properties | Back Directory | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
-15°C
| [solubility ]
DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml | [form ]
A crystalline solid | [pka]
3.38±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces relaxation in precontracted rat arteries in a concentration-dependent manner, an effect that can be reduced by the nitric oxide synthase inhibitor L-NNA (Item No. 80220).1 It inhibits keratinocyte growth in the presence and absence of growth factors.2 PAR2 (1-6) inhibits LPS-induced pulmonary neutrophil influx and increases in matrix metalloproteinase-2 (MMP-2) activity in mice.3WARNING This product is not for human or veterinary use. |
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| Company Name: |
Nextpeptide Inc
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+86-0571-81612335 +8613336028439 |
| Website: |
http://www.nextpeptide.com/ |
| Company Name: |
Lotusland Life Sciences
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| Telephone: |
+8615821988213 |
| Website: |
https://www.chemicalbook.com/manufacturer/shanghai-longyu-biotechnology-164/ |
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