| Identification | Back Directory | [Name]
2-Propenamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-3-(3,5-dibromo-4-methoxyphenyl)-, (2E)-, 2,2,2-trifluoroacetate (1:3) | [CAS]
1643593-28-5 | [Synonyms]
IanthelliformisamineA TFA Ianthelliformisamine-A TFA Ianthelliformisamine A TFA Ianthelliformisamine A TFA salt 2-Propenamide, N-[3-[[4-[(3-aminopropyl)amino]butyl]amino]propyl]-3-(3,5-dibromo-4-methoxyphenyl)-, (2E)-, 2,2,2-trifluoroacetate (1:3) | [Molecular Formula]
C22H33Br2F3N4O4 | [MDL Number]
MFCD30146220 | [MOL File]
1643593-28-5.mol | [Molecular Weight]
634.33 |
| Hazard Information | Back Directory | [Description]
Ianthelliformisamine A TFA is an antibiotic enhancer against resistant Gram-negative bacteria. | [Uses]
Ianthelliformisamine A TFA is an antibiotic enhancer with activity against resistant Gram-negative bacteria. Ianthelliformisamine A TFA exhibits bactericidal activity against Staphylococcus aureus with an IC50 value of 3.8 μM (minimum inhibitory concentration = 25 μM). The biological activity of Ianthelliformisamine A TFA is derived from the structural variation of its synthetic derivatives and its coupling reaction with different amino ester derivatives[1]. | [References]
[1] Synthesis and antibacterial activities of marine natural product ianthelliformisamines and subereamine synthetic analogues DOI:10.1016/j.bmcl.2021.127883 |
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