ChemicalBook--->CAS DataBase List--->164669-07-2

164669-07-2

164669-07-2 Structure

164669-07-2 Structure
IdentificationBack Directory
[Name]

PKTPKKAKKL
[CAS]

164669-07-2
[Synonyms]

PKTPKKAKKL
CDK5 SUBSTRATE
CDK5 SUBSTRATE [PKTPKKAKKL]
ZSZMVAFYNVHXHA-BJSZDZKQSA-N
PRO-LYS-THR-PRO-LYS-LYS-ALA-LYS-LYS-LEU
H-PRO-LYS-THR-PRO-LYS-LYS-ALA-LYS-LYS-LEU-OH
L-Leucine, L-prolyl-L-lysyl-L-threonyl-L-prolyl-L-lysyl-L-lysyl-L-alanyl-L-lysyl-L-lysyl-
[Molecular Formula]

C53H99N15O12
[MDL Number]

MFCD08459410
[MOL File]

164669-07-2.mol
[Molecular Weight]

1138.45
Chemical PropertiesBack Directory
[Boiling point ]

1466.5±65.0 °C(Predicted)
[density ]

1.209±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 10 mg/ml; DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

A crystalline solid
[pka]

3.37±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

Cyclin-dependent kinase 5 (Cdk5) is a serine/threonine kinase that is predominantly active in neuronal tissues. With p25 or p35, Cdk5 phosphorylates a range of proteins, including histone H1 and tau. Cdk5 substrate is a synthetic peptide (PKTPKKAKKL) corresponding to a sequence of histone H1. It is phosphorylated by Cdk5 with a Km value of 5 μM.
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