| Identification | Back Directory | [Name]
Benzenebutanoic acid, α,2-diamino-5-chloro-γ-oxo- | [CAS]
164789-02-0 | [Synonyms]
Benzenebutanoic acid, α,2-diamino-5-chloro-γ-oxo- | [Molecular Formula]
C10H11ClN2O3 | [MOL File]
164789-02-0.mol | [Molecular Weight]
242.66 |
| Hazard Information | Back Directory | [Uses]
KAT-IN-2 (7) is a potent and selective kynurenine aminotransferase II (KATII) inhibitor[1][2]. | [References]
[1] Roberto Pellicciari, et al. Modulators of the kynurenine pathway of tryptophan metabolism: synthesis and preliminary biological evaluation of (S)-4-(ethylsulfonyl)benzoylalanine, a potent and selective kynurenine aminotransferase II (KAT II) inhibitor. ChemMedChem. 2006 May;1(5):528-31. DOI:10.1002/cmdc.200500095
[2] M Varasi, et al. Derivatives of kynurenine as inhibitors of rat brain kynurenine aminotransferase. European Journal of Medicinal Chemistry. Volume 31, Issue 1, 1996, Pages 11-21. |
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