| Identification | Back Directory | [Name]
1H-Pyrrolo[3,2-c]quinoline, 1-[(3-fluorophenyl)sulfonyl]-4-(1-piperazinyl)- | [CAS]
1648745-46-3 | [Synonyms]
FPPQ
1H-Pyrrolo[3,2-c]quinoline, 1-[(3-fluorophenyl)sulfonyl]-4-(1-piperazinyl)- | [Molecular Formula]
C21H19FN4O2S | [MOL File]
1648745-46-3.mol | [Molecular Weight]
410.46 |
| Hazard Information | Back Directory | [Uses]
FPPQ is a dual-acting 5-HT3 (Ki = 0.9 nM) and 5-HT6 (Ki = 3 nM) receptor antagonist with antipsychotic and procognitive properties. | [References]
[1] Zajdel P, et al. Structure-Based Design and Optimization of FPPQ, a Dual-Acting 5-HT3 and 5-HT6 Receptor Antagonist with Antipsychotic and Procognitive Properties. J Med Chem. 2021 Sep 23;64(18):13279-13298. DOI:10.1021/acs.jmedchem.1c00224 |
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