| Identification | Back Directory | [Name]
3,5-Pyridinedicarboxylic acid, 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethyl-, 3-(2-methoxyethyl) 5-(1-methylethyl) ester | [CAS]
165187-25-7 | [Synonyms]
MEM1003 MEM-1003 MEM 1003 BAY-Z4406 BAY-Z-4406 BAY Z-4406 (Rac)-MEM1003 (Rac)MEM 1003,(Rac) MEM 1003 3,5-Pyridinedicarboxylic acid, 4-(2-chloro-3-cyanophenyl)-1,4-dihydro-2,6-dimethyl-, 3-(2-methoxyethyl) 5-(1-methylethyl) ester | [Molecular Formula]
C22H25ClN2O5 | [MDL Number]
MFCD00940513 | [MOL File]
165187-25-7.mol | [Molecular Weight]
432.9 |
| Chemical Properties | Back Directory | [Boiling point ]
540.6±50.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 125 mg/mL (288.75 mM; ultrasonic and warming and heat to 80°C) | [form ]
Solid | [pka]
2.68±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
(Rac)-MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca2+ channel antagonist and has the potential for Alzheimer’s disease research[1]. | [References]
[1] Gregory M Rose, et al. Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73. DOI:10.1016/j.neurobiolaging.2006.03.006 |
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