| Identification | Back Directory | [Name]
Methanesulfinic acid, 1,1-difluoro-, sodium salt (1:1) | [CAS]
1661836-10-7 | [Synonyms]
Sodiumfluoromethanesulfinate
Methanesulfinic acid, 1,1-difluoro-, sodium salt (1:1) | [Molecular Formula]
CH2FNaO2S | [MOL File]
1661836-10-7.mol | [Molecular Weight]
120.079 |
| Hazard Information | Back Directory | [Uses]
Sodium fluoromethanesulfinate is used as efficient radical fluoroalkylating reagents,it is able to react with conjugated N-arylsulfonated amides to yield the desired fluoroalkylamides.
| [Reactions]
Ref. 1) He, Z.; Tan, P.; Ni, C.; Hu, J. Org. Lett. 2015, 17, 1838 –1841. (The invention of HCF2SO2Na and H2CFSO2Na as radical fluoroalkylation reagents)
2) Dai, P.; Yu, X.; Teng, P.; Zhang, W.-H.; Deng, C. Org. Lett. 2018, 20, 6901-6905.
3) Zhang, W. et al. Nat. Commun. 2020, 11, art. no. 638. (HCF2SO2Na was referred to as Hu’s reagent) |
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