| Identification | Back Directory | [Name]
Thalidasine | [CAS]
16623-56-6 | [Synonyms]
Thalidasin
Thalidasine
O-Methylthalfetidine
6,6',7,7',12-Pentamethoxy-2,2'-dimethylthalidasan
19H-2,3,7-[1,3]Butadien[1]yl[4]ylidene-9,12-etheno-14,18-metheno-4H-pyrido[2,3,4-tu]-1,13,6-benzodioxaazacyclodocosine, 5,6,7,8,19a,20,21,22-octahydro-15,24,25,31,32-pentamethoxy-6,20-dimethyl-, (7S,19aS)- | [Molecular Formula]
C39H44N2O7 | [MDL Number]
MFCD01682475 | [MOL File]
16623-56-6.mol | [Molecular Weight]
652.78 |
| Hazard Information | Back Directory | [Description]
Thalictrum dasycarpum yields this bisbenzy1isoquino1ine alkaloid which is
obtained as an amorphous powder. It has [α]27D- 70° (c 0.89, MeOH) and gives
an ultraviolet spectrum with absorption maxima at 275 and 282 IT1J1. The
alkaloid yields a crystalline oxalate, m.p. 160-2°C; picrate, m.p. 175-7°C and
the methiodide, m.p. 182-3°C. Five methoxyl groups are present and two
methylimino groups. | [Uses]
Thalidasine (compound 3) is a bisbenzyltetrahydroisoquinoline alkaloid. Thalidasine is a anticancer agent against human colon adenocarcinoma cells. Thalidasine exhibits antileishmanial activity and can be used for Leishmania infection research research[1]. | [Definition]
ChEBI: Thalidasine is a member of isoquinolines and a bisbenzylisoquinoline alkaloid. | [References]
Kupchan et al., 1. Amer. Chem. Soc., 89,3075 (1967) |
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