| Identification | Back Directory | [Name]
1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- | [CAS]
166374-48-7 | [Synonyms]
Adentri
1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl- | [Molecular Formula]
C18H24N4O3 | [MDL Number]
MFCD04113212 | [MOL File]
166374-48-7.mol | [Molecular Weight]
344.41 |
| Hazard Information | Back Directory | [Description]
Adentri, also known as BG-9719 and CVT-124, is a novel adenosine A1 receptor antagonist with unique diuretic activity. | [Uses]
Adentri (CVT-124) is a potent and A1-adenosine selective antagonist with a Ki of 0.45 nM at cloned human A1-receptors. Adentri can be utilized in cardiovascular research[1]. | [References]
[1] Pfister JR, et al. Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine. J Med Chem. 1997 Jun 6;40(12):1773-8. DOI:10.1021/jm970013w |
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