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166374-48-7

166374-48-7 Structure

166374-48-7 Structure
IdentificationBack Directory
[Name]

1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl-
[CAS]

166374-48-7
[Synonyms]

Adentri
1H-Purine-2,6-dione, 3,9-dihydro-8-(1S,2R,4S,5S,6R)-3-oxatricyclo[3.2.1.02,4]oct-6-yl-1,3-dipropyl-
[Molecular Formula]

C18H24N4O3
[MDL Number]

MFCD04113212
[MOL File]

166374-48-7.mol
[Molecular Weight]

344.41
Chemical PropertiesBack Directory
[Boiling point ]

596.1±56.0 °C(Predicted)
[density ]

1.320±0.06 g/cm3(Predicted)
[pka]

8.85±0.70(Predicted)
Hazard InformationBack Directory
[Description]

Adentri, also known as BG-9719 and CVT-124, is a novel adenosine A1 receptor antagonist with unique diuretic activity.
[Uses]

Adentri (CVT-124) is a potent and A1-adenosine selective antagonist with a Ki of 0.45 nM at cloned human A1-receptors. Adentri can be utilized in cardiovascular research[1].
[References]

[1] Pfister JR, et al. Synthesis and biological evaluation of the enantiomers of the potent and selective A1-adenosine antagonist 1,3-dipropyl-8-[2-(5,6-epoxynorbonyl)]-xanthine. J Med Chem. 1997 Jun 6;40(12):1773-8. DOI:10.1021/jm970013w
166374-48-7 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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