| Identification | Back Directory | [Name]
(TRIPHENYLPHOSPHORANYLIDENE)ACETONITRILE | [CAS]
16640-68-9 | [Synonyms]
NSC 135204
(CYANOMETHYLENE)TRIPHENYLPHOSPHORANE
Triphenyl(cyanomethylene)phosphorane
Triphenylphosphoranylidenacetonitrile
Cyanomethyltriphenylphosphonium ylide
(TRIPHENYLPHOSPHORANYLIDENE)ACETONITRILE
(Cyano)(triphenylphosphoranylidene)methane
2-(triphenylphosphoranylidene)acetonitrile
2-(triphenyl-l5-phosphanylidene)acetonitrile
(Triphenylphosphoranylidene)acetonitrile,96%
Cyanomethylene triphenylphosphorane, min. 97 %
(Triphenylphosphoranylidene)acetonitrile,(Cyanomethylene)triphenylphosphorane | [EINECS(EC#)]
240-689-7 | [Molecular Formula]
C20H16NP | [MDL Number]
MFCD00567633 | [MOL File]
16640-68-9.mol | [Molecular Weight]
301.32 |
| Chemical Properties | Back Directory | [Appearance]
off-white to light yellow crystalline powder | [Melting point ]
189-195 °C(lit.)
| [Boiling point ]
465.3±28.0 °C(Predicted) | [density ]
1.16±0.1 g/cm3(Predicted) | [Fp ]
>110°C | [storage temp. ]
Refrigerator | [form ]
powder to crystal | [color ]
White to Orange to Green | [InChI]
InChI=1S/C20H16NP/c21-16-17-22(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20/h1-15,17H | [InChIKey]
APISVOVOJVZIBA-UHFFFAOYSA-N | [SMILES]
C(#N)C=P(C1=CC=CC=C1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| Hazard Information | Back Directory | [Chemical Properties]
off-white to light yellow crystalline powder | [Uses]
(Triphenylphosphoran?ylidene)?acetonitrile is a reactant in the synthesis of largazole analogues which displays potent cell growth inhibition and cytotoxicity. As well, is used in the synthesis of monoterpene derivatives against leukemia. | [Acquired resistance]
(Triphenylphosphoranylidene)acetonitrile may be generated by deprotonation of the corresponding phosphonium salt, by cyanation of Methylenetriphenylphosphorane with p-tolyl cyanate, or by the reaction of Acrylonitrile with (Methoxycarbonylmethylene)triphenylphosphorane.
 | [reaction suitability]
reaction type: C-C Bond Formation |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [RIDADR ]
UN 2811 6.1/PG III | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29319090 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
|
|