| Identification | Back Directory | [Name]
(+/-)-Narwedine | [CAS]
1668-86-6 | [Synonyms]
(4aR
8aR)-rel-
DL-Narwedine
L(+)-Narwedine
(+/-) NAWEDINE
(+/-s)Narwedin
6H-Benzofuro[3a
(+/-)-Narwedine
Narwedine,racemic
2-ef][2]benzazepin-6-one
(+/-)-3-Deoxy-3-oxogalanthamine
(±)-Narwedine (±-Galanthaminone)
(±)-Narwedine (±-Galanthaminone)
12-hexahydro-3-Methoxy-11-Methyl-
GalantaMine interMediate (dl-Narwedine)
(4aR,8aR)-3-Methoxy-11-methyl-4a,5,9,10,11,12-hexahydro-6H-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-one
6H-Benzofuro[3a,3,2-ef][2]benzazepin-6-one, 4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-, (4aR,8aR)-rel- | [Molecular Formula]
C17H19NO3 | [MDL Number]
MFCD13193038 | [MOL File]
1668-86-6.mol | [Molecular Weight]
285.341 |
| Chemical Properties | Back Directory | [Melting point ]
198-199 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
397.4±42.0 °C(Predicted) | [density ]
1.28 | [pka]
7.84±0.20(Predicted) | [InChI]
InChI=1/C17H19NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,14H,7-10H2,1-2H3/t14-,17-/s3 | [InChIKey]
QENVUHCAYXAROT-OALMKZFLNA-N | [SMILES]
N1(C)CC2=CC=C(OC)C3O[C@@]4([H])[C@](C=CC(=O)C4)(C2=3)CC1 |&1:11,13,r| | [Uses]
Narwedine is the biogenetic precursor of galanthamine, has been studied as a respiratory stimulator. It increases the amplitude and decreases the frequency of cardiac contractions and would therefore be of value in reducing blood loss during surgery. It also inhibits the action of narcotics and hypnotics, and increases the analgesic effect of morphine as well as the pharmacological effects of caffeine, carbazole, arecoline, and nicotine. | [CAS DataBase Reference]
1668-86-6 |
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