| Identification | Back Directory | [Name]
2'-Deoxy-2'-fluoroisocytidine | [CAS]
1668560-65-3 | [Synonyms]
2'-Deoxy-2'-fluoroisocytidine
2’-Deoxy-2’-fluoroisocytidine
2-Amino-1-(2-deoxy-2-fluoro-β-D-ribofuranosyl)-4(1H)-pyrimidinone
4(1H)-Pyrimidinone, 2-amino-1-(2-deoxy-2-fluoro-β-D-ribofuranosyl)- | [Molecular Formula]
C9H12FN3O4 | [MDL Number]
MFCD25542472 | [MOL File]
1668560-65-3.mol | [Molecular Weight]
245.21 |
| Hazard Information | Back Directory | [Uses]
2-Deoxy-2’-fluoroisocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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