166967-84-6

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166967-84-6 Structure

Identification	Back Directory
[Name] NTE-122 DIHYDROCHLORIDE
[CAS] 166967-84-6
[Synonyms] NTE-122 DIHYDROCHLORIDE trans-1,4-Bis[[1-cyclohexyl-3-(4-dimethylaminophenyl)ureido]methyl]cyclohexane dihydrochloride
[Molecular Formula] C38Cl2H60N6O2
[MDL Number] MFCD07370144
[MOL File] 166967-84-6.mol
[Molecular Weight] 703.83

Chemical Properties	Back Directory
[Melting point ] 169-170.8 °C

Hazard Information	Back Directory
[Uses] NTE-122 (dihydrochloride) is an inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with the IC50 in liver and aorta of cholesterol-fed rabbits of 7.6nM, 4.4nM and 9.6 nM, respectively, that plays an important role in atherosclerosis[1].
[References] [1] Y Azuma, et al. NTE-122, an Acyl-CoA:Cholesterol Acyltransferase Inhibitor, Prevents the Progression of Atherogenesis in Cholesterol-Fed Rabbits. Jpn J Pharmacol. 2001 May;86(1):120-3. DOI:10.1254/jjp.86.120

166967-84-6 suppliers list

Company Name:	Beijing Biocreative Technology Co., Ltd.
Tel:	15522676233
Website:	www.bestbaiao.com/

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