| Identification | Back Directory | [Name]
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE | [CAS]
167144-79-8 | [Synonyms]
R-96544HCl
R-96544 HYDROCHLORIDE
R96544 hydrochloride,R 96544 hydrochloride
(3R,5R)-5-(2-(2-(3-methoxyphenethyl)phenoxy)ethyl)-1-methylpyrrolidin-3-ol
3-Pyrrolidinol, 5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-, (3R,5R)-
(2R,4R)-5-(2-(2-(2-(3-Methoxyphenyl)ethyl)phenoxy)ethyl)-1-methyl-3-pyrrolidinolhydrochloride
(3R,5R)-5-[2-[2-[2-(3-METHOXYPHENYL)ETHYL]PHENOXY]ETHYL]-1-METHYL-3-PYRROLIDINOL HYDROCHLORIDE | [Molecular Formula]
C22H29NO3 | [MDL Number]
MFCD06407939 | [MOL File]
167144-79-8.mol | [Molecular Weight]
355.47 |
| Hazard Information | Back Directory | [Uses]
R-96544 Hydrochloride is a the active form of a novel 5-HT2A receptor antagonist R-102444. It inhibits the platelet aggregation induced by serotonin (5-hydroxytryptamine, 5-HT). | [Definition]
ChEBI: (3R,5R)-5-[2-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-3-pyrrolidinol is a stilbenoid. | [Biological Activity]
Potent, selective 5-HT 2 receptor antagonist; displays some selectivity for 5-HT 2A receptors (K i = 1.6 nM). IC 50 values are 2.2, 310, 2400, 3700, > 5000 and > 5000 nM for 5-HT 2 , a 1 -adrenergic, D 2 dopamine, 5-HT 1 , 5-HT 3 and b-adrenergic receptors respectively. Inhibits 5-HT-induced platelet aggregation and pressor responses in vivo . | [storage]
Store at RT |
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Energy Chemical
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BIOTREND GmbH
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www.biotrend.de |
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Labinova AB
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