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1675-02-1

1675-02-1 Structure

1675-02-1 Structure
IdentificationBack Directory
[Name]

(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione
[CAS]

1675-02-1
[Synonyms]

Erythromycin C - API
Erythromycin Impurity 6
Erythromycin Impurity 14
3'-O-Demethylerythromycin
Erythromycin C (E1320000)
3"-O-DeMethylerythroMycin A
Erythromycin, 3''-O-demethyl-
Erythromycin C (Erythromycin Impurity 3)
(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylaChemicalbookmino-3-hydroxy-6-methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-
(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-4-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6 -dimethyl-oxan-2-yl]oxy-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-m ethyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexameth yl-1-oxacyclotetradecane-2,10-dione
Erythromycin C/(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-(((2R,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexa
[Molecular Formula]

C36H65NO13
[MDL Number]

MFCD22666225
[MOL File]

1675-02-1.mol
[Molecular Weight]

719.9
Chemical PropertiesBack Directory
[Melting point ]

121-125 °C
[Boiling point ]

826.2±65.0 °C(Predicted)
[density ]

1.23±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble; Water: limited solubility
[form ]

neat
[pka]

13.09±0.70(Predicted)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26
Hazard InformationBack Directory
[Description]

Erythromycin C is an intermediate in the biosynthesis of erythromycin . It is also a potential impurity found in commercial preparations of erythromycin. Erythromycin C is half as active or less than erythromycin A or B against most Gram-positive and Gram-negative bacteria tested.
[Uses]

Erythromycin (E649950) impurity. A related substance in Erythromycin drug.
[Uses]

Erythromycin C (3’’-O-demethylerythromycin A) is a minor co-metabolite of erythromycin produced by Saccharopolyspora erythreae. Erythromycin C exhibits a narrower spectrum of antibiotic activity and is much less active than erythromycins A and B.
[Definition]

ChEBI: Erythromycin C is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is functionally related to an erythronolide A. It is a conjugate base of an erythromycin C(1+).
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