Identification | Back Directory | [Name]
Cy3 Methyltetrazine | [CAS]
1676067-48-3 | [Synonyms]
Cy3 Methyltetrazine Trisulfo-Cy3 methyltetrazine Cy3 Methyltetrazine (CCT-1018) | [Molecular Formula]
C42H49N7O10S3 | [MOL File]
1676067-48-3.mol | [Molecular Weight]
908.07 |
Hazard Information | Back Directory | [Uses]
Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures[1][2]. | [References]
[1] Cy3 Methyltetrazine. [2] Vera F C Ferreira, et al. In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry. Bioconjug Chem. 2021 Jan 20;32(1):121-132. |
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