| Chemical Properties | Back Directory | [Boiling point ]
2726.8±65.0 °C(Predicted) | [density ]
1.49±0.1 g/cm3(Predicted) | [Sequence]
H-Asp-Thr-Asn-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Lys-Cys-Cys-Asn-Asn-Ser-Gln-Cys-Gly-Ile-Cys-Cys-Lys-Thr-OH trifluoroacetate salt |
| Hazard Information | Back Directory | [Uses]
Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation[1]. | [IC 50]
MMP-9; cathepsin K | [References]
[1] Zhao GY, et al. Effects of mouse hepcidin 1 treatment on osteoclast differentiation and intracellular iron concentration. Inflammation. 2015 Apr;38(2):718-27. DOI:10.1007/s10753-014-9982-2 |
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