| Identification | Back Directory | [Name]
AGITOXIN-2 | [CAS]
168147-41-9 | [Synonyms]
AGTX2
RAGTX2
AGITOXIN-2
AGITOXIN-2, RECOMBINANT
Agitoxin-2 from scorpion venom | [Molecular Formula]
C169H278N54O48S8 | [MDL Number]
MFCD00285471 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [form ]
lyophilized powder
| [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
Gly-Val-Pro-Ile-Asn-Val-Ser-Cys-Thr-Gly-Ser-Pro-Gln-Cys-Ile-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro-Lys (Disulfide bridge:Cys8-Cys28;Cys14-Cys33;Cys18-Cys35) |
| Hazard Information | Back Directory | [Uses]
Agitoxin-2 is a K+ channel inhibitor, with IC50 values of 201 pM and 144 pM for mKV1.3 and mKV1.1, respectively)[1][2]. | [storage]
Store at -20°C | [References]
[1] M L Garcia, et al. Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry. 1994 Jun 7;33(22):6834-9. DOI:10.1021/bi00188a012
[2] Raveendra Anangi, et al. Recombinant expression of margatoxin and agitoxin-2 in Pichia pastoris: an efficient method for production of KV1.3 channel blockers. DOI:10.1371/journal.pone.0052965 |
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Fuan Bio
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15002819872 |
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fuanbio.com |
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