| Identification | Back Directory | [Name]
GR 203040 | [CAS]
168398-02-5 | [Synonyms]
GR 203040
GR-203040 HCl
GR 203040; GR203040
GR 203040(LS-113867)
GR203040 >=98% (HPLC)
GR-203040 hydrochloride
GR 203040 HCl,GR203040 HCl
(2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride
(2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine hydrochloride (1:2)
3-PiperidinaMine, N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]Methyl]-2-phenyl-, (Hydrochloride) (1:2), (2S,3S)- | [Molecular Formula]
C20H25ClN6O | [MOL File]
168398-02-5.mol | [Molecular Weight]
400.91 |
| Hazard Information | Back Directory | [Uses]
GR203040 is an orally active NK1 receptor antagonist with a pKi of 10.3. GR203040 shows potent antiemetic activity[1]. | [storage]
Store at -20°C | [References]
[1] Ward P, et al. Discovery of an orally bioavailable NK1 receptor antagonist, (2S,3S)-(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (GR203040), with potent antiemetic activity. J Med Chem. 1995 Dec 22;38(26):4985-92. DOI:10.1021/jm00026a005 |
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