| Identification | Back Directory | [Name]
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate | [CAS]
1690176-75-0 | [Synonyms]
IUN76750
PAR-2-IN-1
PAR-2 inhibitor
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-car
Methyl 8-(tert-butyl)-6-chloroimidazo[1,2-b]pyridazine-2-carboxylate
Imidazo[1,2-b]pyridazine-2-carboxylic acid, 6-chloro-8-(1,1-dimethylethyl)-, methyl ester
Inhibitor,PAR2IN1,anti-inflammatory,anticancer,PAR 2 IN 1,inhibit,PAR2,Thrombin receptors,Protease Activated Receptor (PAR) | [Molecular Formula]
C12H14ClN3O2 | [MDL Number]
MFCD28144723 | [MOL File]
1690176-75-0.mol | [Molecular Weight]
267.71 |
| Chemical Properties | Back Directory | [density ]
1.31±0.1 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
DMSO : 83.33 mg/mL (311.27 mM; Need ultrasonic) | [form ]
Solid | [pka]
0.85±0.30(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
PAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor with anti-inflammatory and anticancer effects[1]. | [IC 50]
PAR2 | [storage]
Store at -20°C | [References]
[1] Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO2015048245A1. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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