| Identification | Back Directory | [Name]
Propanamide, 3-[(2-chlorophenyl)amino]-2-cyano-3-thioxo-N-[3-(trifluoromethyl)phenyl]- | [CAS]
169120-56-3 | [Synonyms]
Propanamide, 3-[(2-chlorophenyl)amino]-2-cyano-3-thioxo-N-[3-(trifluoromethyl)phenyl]- | [Molecular Formula]
C17H11ClF3N3OS | [MOL File]
169120-56-3.mol | [Molecular Weight]
397.8 |
| Chemical Properties | Back Directory | [density ]
1.509±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
14.70±0.70(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
DP00477 is a potent IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor with an IC50 value of 7.0 μM. DP00477 has the potential for the research of cancer[1]. | [IC 50]
IDO1: 7.0 μM (IC50) | [References]
[1] R?hrig UF, et al. Detailed analysis and follow-up studies of a high-throughput screening for indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. Eur J Med Chem. 2014 Sep 12;84:284-301. DOI:10.1016/j.ejmech.2014.06.078 |
|
|