| Chemical Properties | Back Directory | [Boiling point ]
464.5±35.0 °C(Predicted) | [density ]
1.126±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
10.01±0.15(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Alkyne-phenol (Alk-Ph) is a clickable ascorbate peroxidase 2 (APEX2) probe. Alkyne-phenol substantially improves APEX-labeling efficiency in intact yeast cells, as it is more cell wall-permeant than APEX2 substrate biotin-phenol (BP). Alkyne-phenol also facilitates the identification of APEX-labeling sites, allowing the unambiguous assignment of membrane topology of mitochondrial proteins[1]. Alkyne-phenol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Li Y, et al. A Clickable APEX Probe for Proximity-Dependent Proteomic Profiling in Yeast. Cell Chem Biol. 2020;27(7):858-865.e8. DOI:10.1016/j.chembiol.2020.05.006 |
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| Company Name: |
NewCan Biotech Limited
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| Telephone: |
+86-0571-86912261 +86-15658003402 |
| Website: |
https://www.newcanbio.com/ |
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