| Identification | Back Directory | [Name]
icrocaptide | [CAS]
169543-49-1 | [Synonyms]
ITF1697
ITF-1697
ITF 1697
Icrocaptide
L-Arginine, glycyl-N2-ethyl-L-lysyl-L-prolyl- | [Molecular Formula]
C21H40N8O5 | [MOL File]
169543-49-1.mol | [Molecular Weight]
484.59 |
| Hazard Information | Back Directory | [Uses]
Icrocaptide (ITF1697) is a stable Lys-Pro-containing peptide that inhibits the intracellular Ca2+-dependent fusion of Weibel-Palade bodies with the plasma membrane. Icrocaptide exerts its activity at the early stages of endothelial activation and inhibits P-selectin and von Willebrand factor secretion. Icrocaptide can be used for the study of a variety of microvascular disorders[1]. | [References]
[1] Silvia Bertuglia, et al. ITF1697, a stable Lys-Pro-containing peptide, inhibits weibel-palade body exocytosis induced by ischemia/reperfusion and pressure elevation. Mol Med. 2007 Nov-Dec;13(11-12):615-24. DOI:10.2119/2007-00079.Bertuglia |
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Fuan Bio
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15002819872 |
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