169901-27-3

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169901-27-3 Structure

Identification	Back Directory
[Name] DC-1
[CAS] 169901-27-3
[Synonyms] DC-1 1H-Indole-2-carboxamide, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-5-yl]-5-[(3-mercapto-1-oxopropyl)amino]-
[Molecular Formula] C34H28ClN5O4S
[MDL Number] MFCD31729541
[MOL File] 169901-27-3.mol
[Molecular Weight] 638.14

Hazard Information	Back Directory
[Uses] DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.
[IC 50] Duocarmycins
[References] [1] Kovtun YV, et al. Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen. Cancer Res. 2006 Mar 15;66(6):3214-21. DOI:10.1021/jm201284m

169901-27-3 suppliers list

Company Name:	Hangzhou Huarong Pharm Co., Ltd.
Tel:	571-86758373 +8613588754946 , +8613588754946
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Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 18892239720
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Company Name:	Fan De(Beijing) Biotechnology Co., Ltd.
Tel:	15911056312
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Company Name:	Shanghai Haoyuan Chemexpress Co., Ltd.
Tel:	021-51870955
Website:	www.chemexpress.com.cn

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840 15801484223;
Website:	http://www.jm-bio.com/

Company Name:	Hubei wei shi reagent group ltd., company
Tel:	027-59102966 18717199209
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