| Hazard Information | Back Directory | [Uses]
vaccine development | [Biological Activity]
Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4). It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL)-1βhowever not as efficient as lipopolysaccharide (LPS). MPLA improves immune response during bacterial sepsis infection. |
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