| Identification | Back Directory | [Name]
(5S,6R,15R)-5,6,15-TRIHYDROXY-7,9,13-TRANS-11-CIS-EICOSATETRAENOIC ACID | [CAS]
171030-11-8 | [Synonyms]
15(R)-LXA4
LXA4-15-EPI
AT-Lipoxin A4
15(R)-Lipoxin A4
15-epi-Lipoxin A4
LIPOXIN A4, 15-EPI
ASPIRIN-TRIGGERED LXA4
5(S),6(R),15(R)-Lipoxin A4
IXAQOQZEOGMIQS-JEWNPAEBSA-N
Lipoxin A, 15-epi - CAS 171030-11-8 - Calbiochem
15(R)Lipoxin A4,15(R) Lipoxin A4,15(R)-Lipoxin A-4
(5S,6R,15R)-5,6,15-TRIHYDROXY-7,9,13-TRANS-11-CIS-EICOSATETRAENOIC ACID
7,9,11,13-Eicosatetraenoic acid, 5,6,15-trihydroxy-, (5S,6R,7E,9E,11Z,13E,15R)- | [Molecular Formula]
C20H32O5 | [MDL Number]
MFCD02259382 | [MOL File]
171030-11-8.mol | [Molecular Weight]
352.47 |
| Chemical Properties | Back Directory | [Boiling point ]
589.4±50.0 °C(Predicted) | [density ]
1.096±0.06 g/cm3(Predicted) | [storage temp. ]
= -70C | [solubility ]
DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml | [form ]
Liquid | [pka]
4.67±0.10(Predicted) | [InChIKey]
IXAQOQZEOGMIQS-CRSXNMAESA-N | [SMILES]
OC(C(O)\C=C\C=C\C=C\C=C\C(O)CCCCC)CCCC(=O)O |
| Hazard Information | Back Directory | [Uses]
Lipoxin A4, 15-epi is a LXA4 analog that is more potent and metabolically stable than LXA4 shown to block IL-8 release. | [Definition]
ChEBI: 15-epi-lipoxin A4 is a C20 hydroxy polyunsaturated fatty acid having (5S)-, (6R)- and (15R)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds. It has a role as a metabolite. It is a lipoxin, a long-chain fatty acid and a hydroxy polyunsaturated fatty acid. | [Biological Activity]
Cell permeable: no''Primary Target
Exhibits anti-inflammatory properties''Product does not compete with ATP.''Reversible: no | [IC 50]
STAT6 |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck Millipore
|
| Tel: |
1-400-889-1988 400-889-1988 |
| Website: |
http://www.merckmillipore.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|