| Identification | Back Directory | [Name]
2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-, calcium salt (2:1), [4S-(4α,4aα,5aα,6β,12aα)]- (9CI) | [CAS]
17146-81-5 | [Synonyms]
Demeclocycline calcium
2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-, calcium salt (2:1), [4S-(4α,4aα,5aα,6β,12aα)]- (9CI) | [Molecular Formula]
C21H23CaClN2O8 | [MOL File]
17146-81-5.mol | [Molecular Weight]
506.95 |
| Hazard Information | Back Directory | [Uses]
Demeclocycline (calcium) is an orally active tetracycline antibiotic that inhibits the binding of aminoacyl tRNA by binding to the 30S ribosomal subunit, thereby affecting protein synthesis. Demeclocycline (calcium) exhibits antibacterial activity against a broad spectrum of bacterial infections[1][2]. | [References]
[1] I Chopra, et al. Tetracyclines, molecular and clinical aspects. J Antimicrob Chemother. 1992 Mar;29(3):245-77. DOI:10.1093/jac/29.3.245
[2] D Schnappinger, et al. Tetracyclines: antibiotic action, uptake, and resistance mechanisms. Arch Microbiol. 1996 Jun;165(6):359-69. DOI:10.1007/s002030050339 |
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