| Identification | Back Directory | [Name]
1-Pentanone, 5-(3R)-1,2-dithiolan-3-yl-1-[hexahydro-4-(5-isoquinolinylsulfonyl)-1H-1,4-diazepin-1-yl]- | [CAS]
1715039-50-1 | [Synonyms]
L-F001 >=98% (HPLC)
1-Pentanone, 5-(3R)-1,2-dithiolan-3-yl-1-[hexahydro-4-(5-isoquinolinylsulfonyl)-1H-1,4-diazepin-1-yl]- | [Molecular Formula]
C22H29N3O3S3 | [MOL File]
1715039-50-1.mol | [Molecular Weight]
479.67 |
| Chemical Properties | Back Directory | [Boiling point ]
706.2±70.0 °C(Predicted) | [density ]
1.312±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
oil | [pka]
4.33±0.13(Predicted) | [color ]
colorless to light brown |
| Hazard Information | Back Directory | [Biological Activity]
L-F001 is a multifunctionalbrain penetrant and potent Rho-associated protein kinase (ROCK) inhibitor th at protects the PC12 cells from paraqu at induced cytotoxicity. L-F001 suppresses neuroinflammation in vitro and in vivo. |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|