| Identification | Back Directory | [Name]
HIS-CYS-LYS-PHE-TRP-TRP | [CAS]
172546-75-7 | [Synonyms]
HCKFWW
HIV INTEGRASE PROTEIN
HIS-CYS-LYS-PHE-TRP-TRP
H-HIS-CYS-LYS-PHE-TRP-TRP-OH
HIV INTEGRASE [IN] INHIBITOR
HIV INTEGRASE PROTEIN INHIBITOR
HIV INTEGRASE PROTEIN INHIBITOR(1)
HIV INTEGRASE PROTEIN INHIBITOR (I)
7:PN:WO2005068492 SEQID:17 unclaimed sequence
L-Tryptophan, L-histidyl-L-cysteinyl-L-lysyl-L-phenylalanyl-L-tryptophyl- | [Molecular Formula]
C46H55N11O7S | [MDL Number]
MFCD00798733 | [MOL File]
172546-75-7.mol | [Molecular Weight]
906.06 |
| Chemical Properties | Back Directory | [Boiling point ]
1395.9±65.0 °C(Predicted) | [density ]
1.367±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [form ]
Solid | [pka]
3.38±0.10(Predicted) | [Sequence]
His-Cys-Lys-Phe-Trp-Trp |
| Hazard Information | Back Directory | [Uses]
His-Cys-Lys-Phe-Trp-Trp is an inhibitor for the human immunodeficiency virus (HIV) integrase with an IC50 of 2 μM[1]. | [References]
[1] Puras Lutzke RA, et al., Identification of a hexapeptide inhibitor of the human immunodeficiency virus integrase protein by using a combinatorial chemical library. Proc Natl Acad Sci U S A. 1995 Dec 5;92(25):11456-60. DOI:10.1073/pnas.92.25.11456 |
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