| Identification | Back Directory | [Name]
LY 272015 HYDROCHLORIDE | [CAS]
172895-15-7 | [Synonyms]
LY272015
LY 272015 HYDROCHLORIDE
LY 272015 HYDROCHLORIDE ISO 9001：2015 REACH
1-(3,4-dimethoxybenzyl)-6-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole HCl
1-[(3,4-dimethoxyphenyl)methyl]-6-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
1-[(3,4-Dimethoxyphenyl)methy]-2,3,4,9-tetrahydro-6-methyl-1H-pyrido[3,4-b]indolehydrochloride
1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-1H-Pyrido[3,4-b]indole hydrochloride (1:1)
1H-Pyrido[3,4-b]indole, 1-[(3,4-dimethoxyphenyl)methyl]-2,3,4,9-tetrahydro-6-methyl-, hydrochloride (1:1) | [Molecular Formula]
C21H25ClN2O2 | [MDL Number]
MFCD00933882 | [MOL File]
172895-15-7.mol | [Molecular Weight]
372.89 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at +4°C | [solubility ]
Soluble to 100 mM in DMSO and to 10 mM in ethanol | [form ]
Powder | [color ]
Off-white to light yellow | [InChI]
1S/C21H24N2O2.ClH/c1-13-4-6-17-16(10-13)15-8-9-22-18(21(15)23-17)11-14-5-7-19(24-2)20(12-14)25-3;/h4-7,10,12,18,22-23H,8-9,11H2,1-3H3;1H | [InChIKey]
BKAZOTIBKRWLQA-UHFFFAOYSA-N | [SMILES]
CC1=CC(C2=C(C(NCC2)CC(C=C3OC)=CC=C3OC)N4)=C4C=C1.Cl |
| Hazard Information | Back Directory | [Uses]
LY 272015 Hydrochloride is a potent and selective serotonin 2B (5HT2B) contractile receptor. | [Biological Activity]
High affinity 5-HT 2B receptor antagonist that displays selectivity over 5-HT 2A and 5-HT 2C receptors (K i values are 0.75, 21.63 and 28.7 nM for 5-HT 2B , 5-HT 2C and 5-HT 2A receptors respectively). Orally active. | [IC 50]
5-HT2B Receptor | [storage]
+4°C |
|
|