| Identification | Back Directory | [Name]
L742001 hydrochloride | [CAS]
174605-64-2 | [Synonyms]
L-742001
L-742001 HCl
L742001 hydrochloride
L-742001 hydrochloride
L-742,001 hydrochloride
L-742001 hydrochloride >=98% (HPLC)
(Z)-4-[1-Benzyl-4-[(4-chlorophenyl)methyl]piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid hydrochloride
(2Z)-4-{1-benzyl-4-[(4-chlorophenyl)methyl]piperidin-4-yl}-2-hydroxy-4-oxobut-2-enoic acid hydrochloride
4-[4-[(4-Chlorophenyl)methyl]-1-(phenylmethyl)-4-piperidinyl]-2-hydroxy-4-oxo-2-butenoic acid hydrochloride | [Molecular Formula]
C23H25Cl2NO4 | [MDL Number]
MFCD22587878 | [MOL File]
174605-64-2.mol | [Molecular Weight]
450.36 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: soluble20mg/mL, clear | [form ]
powder | [color ]
white to beige | [InChI]
1S/C23H24ClNO4.ClH/c24-19-8-6-17(7-9-19)15-23(21(27)14-20(26)22(28)29)10-12-25(13-11-23)16-18-4-2-1-3-5-18;/h1-9,14,26H,10-13,15-16H2,(H,28,29);1H/b20-14-; | [InChIKey]
LMLNSXCRZNNZBT-VSOKSMTPSA-N | [SMILES]
O/C(C(O)=O)=C\C(C(CC1)(CC2=CC=C(Cl)C=C2)CCN1CC3=CC=CC=C3)=O.Cl |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
22-50/53 | [Safety Statements ]
46-60-61 | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| Hazard Information | Back Directory | [Uses]
L-742001 acts as an inhibitor or RNA Polymerase. | [Biochem/physiol Actions]
L-742,001 is an inhibitor of the influenza virus RNA polymerase PA subunit, implicated in several roles, including endonuclease and protease activities as well as viral RNA/complementary RNA promoter binding. L-742,001 inhibits the influenza endonuclease-dependent polymerase activity with an IC50 of 430 nM. |
|
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Sigma-Aldrich
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Novachemistry
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Energy Chemical
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Merck KGaA
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www.sigmaaldrich.cn |
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