| Identification | Back Directory | [Name]
Benzamide, 3-chloro-2-hydroxy-N-[(1S,6R)-6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]- | [CAS]
175448-31-4 | [Synonyms]
Benzamide, 3-chloro-2-hydroxy-N-[(1S,6R)-6-(hydroxymethyl)-2,5-dioxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]- | [Molecular Formula]
C14H10ClNO6 | [MOL File]
175448-31-4.mol | [Molecular Weight]
323.69 |
| Hazard Information | Back Directory | [Uses]
Epoxyquinomicin A is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin A exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 3-12.5 μg/mL. Epoxyquinomicin A exhibits cytotoxicity in cancer cell L1210, B16 and S180 with IC50 of 2-8 μg/mL. Epoxyquinomicin A exhibits anti-inflammatory effects against collagen-induced arthritis[1]. | [References]
[1] Matsumoto N, et al., Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities. J Antibiot (Tokyo). 1997 Nov;50(11):900-5. DOI:10.7164/antibiotics.50.900 |
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