| Identification | Back Directory | [Name]
4H-3,1-Benzoxazin-4-one, 2-(4-iodophenyl)- | [CAS]
176442-56-1 | [Synonyms]
CYP1B1-IN-5
4H-3,1-Benzoxazin-4-one, 2-(4-iodophenyl)- | [Molecular Formula]
C14H8INO2 | [MOL File]
176442-56-1.mol | [Molecular Weight]
349.12 |
| Hazard Information | Back Directory | [Uses]
CYP1B1-IN-5 (Compound 6q) is a potent and selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM[1]. | [IC 50]
CYP1B1: 4.7 nM (IC50); CYP1A1: 190.7 nM (IC50); CYP1A2: 585.7 nM (IC50) | [References]
[1] Yi L, et al. A new class of CYP1B1 inhibitors derived from bentranil. Bioorg Med Chem Lett. 2022 Dec 21;80:129112. DOI:10.1016/j.bmcl.2022.129112 |
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