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17654-19-2

17654-19-2 Structure

17654-19-2 Structure
IdentificationBack Directory
[Name]

R-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-Benzopyran-4-one
[CAS]

17654-19-2
[Synonyms]

(R)-Naringenin
(+)-Naringenin
Naringenin (R)-Isomer
(2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
R-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-Benzopyran-4-one
4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2R)-
[Molecular Formula]

C15H12O5
[MOL File]

17654-19-2.mol
[Molecular Weight]

272.25
Chemical PropertiesBack Directory
[Boiling point ]

577.5±50.0 °C(Predicted)
[density ]

1.485±0.06 g/cm3(Predicted)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Methanol (Slightly, Sonicated)
[form ]

Solid
[pka]

7.52±0.40(Predicted)
[color ]

Off-White to Light Yellow
Hazard InformationBack Directory
[Uses]

(R)-Naringenin is an active flavanone that has been studied as an inhibitor of cytochromes P450 (CYPs), specifically shown to be potent against CYP2C9 and CYP3A. It is found in grape juice as rac Naringenin (N378950) where the (S)-Naringenin (N378955) displays antioxidative, anti-inflammatory and antitumorigenic activities used in the treatment of praquat (PQ)-induced oxidative stress.
[Definition]

ChEBI: (R)-naringenin is the (R)-enantiomer of naringenin. It is an enantiomer of a (S)-naringenin.
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