| Identification | Back Directory | [Name]
5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite | [CAS]
176755-87-6 | [Synonyms]
5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite
5’-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite
Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-5-methyl-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) | [Molecular Formula]
C55H60N5O9P | [MDL Number]
MFCD31537256 | [MOL File]
176755-87-6.mol | [Molecular Weight]
966.08 |
| Hazard Information | Back Directory | [Uses]
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1]. | [References]
[1] Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. DOI:10.4161/cbt.3.11.1308 |
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