| Identification | Back Directory | [Name]
P-TOLYL-BETA-D-GLUCURONIDE | [CAS]
17680-99-8 | [Synonyms]
p-Cresol Glucuronide
p-Tolyl-β-D-glucuronide
p-Tolyl-β-D-glucuronic acid
(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(p-tolyloxy)tetrahydro-2H-pyran-2-carboxylic acid | [Molecular Formula]
C13H16O7 | [MDL Number]
MFCD08277028 | [MOL File]
17680-99-8.mol | [Molecular Weight]
284.26 |
| Chemical Properties | Back Directory | [Melting point ]
138-141°C | [Boiling point ]
549.7±50.0 °C(Predicted) | [density ]
1.524±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C | [solubility ]
H2O: 50 mg/mL, soluble | [form ]
white powder | [pka]
2.80±0.70(Predicted) | [color ]
White | [biological source]
synthetic |
| Hazard Information | Back Directory | [Uses]
P-TOLYL-BETA-D-GLUCURONIDE is a metabolite of o-Cresol (C781910), which is a compound used as a disinfectant and have also been used as antiseptic in surgery.
| [Uses]
p-Cresol Glucuronide, is a metabolite of o-Cresol (C781910), which is a compound used as a disinfectant and have also been used as antiseptic in surgery. | [Definition]
P-TOLYL-BETA-D-GLUCURONIDE is a glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen is replaced by a p-tolyl group.
| [Biological Activity]
p-Cresol glucuronide is generated through a process called glucuronidationwhich is a phase II metabolism reaction in the liver. In this processp-cresola metabolite produced by the gut microbiota during the breakdown of dietary tyrosine and phenylalanineundergoes conjugation with glucuronic acid. This conjugation is catalyzed by the enzyme UDP-glucuronosyltransferase (UGT) to form p-cresol glucuronide. The resulting glucuronide metabolite is then excreted in the urine. This process plays a crucial role in the elimination of p-cresol from the body. | [storage]
-20°C |
|
| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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