ChemicalBook--->CAS DataBase List--->1769-24-0

1769-24-0

1769-24-0 Structure

1769-24-0 Structure
IdentificationBack Directory
[Name]

2-METHYL-4(3H)-QUINAZOLINONE
[CAS]

1769-24-0
[Synonyms]

b101
AURORA KA-3754
2-Methylquinazolone
2-methyl-4-quinazolino
2-Methyl-4-quinazolone
2-methylquinazolin-4-ol
2-Methyl-4-quinazolinone
2-methyl-chinazolinone(4)
4-Quinazolinol, 2-methyl-
2-Methyl-4-oxoquinazoline
2-methyl-4(3h)-quinazolinon
2-methyl-4(1h)-quinazolinon
2-Methyl-4(1H)-quinazolinone
2-methylquinazolin-4(1H)-one
2-METHYL-4(3H)-QUINAZOLINONE
2-methyl-1H-quinazolin-4-one
2-Methyl-3H-quinazolin-4-one
4-Hydroxy-2-methylquinazoline
4(1H)-Quinazolinone, 2-methyl-
4(3H)-Quinazolinone, 2-methyl-
2-Methyl-1,3-diazanaphthalene-4-ol
2-Methyl-4(1H)-quinazolinone
2-Methyl-4-quinazolinol hydrochloride
2-Methyl-3,4-dihydroquinazoline-4-one
[EINECS(EC#)]

217-189-2
[Molecular Formula]

C9H8N2O
[MDL Number]

MFCD00006887
[MOL File]

1769-24-0.mol
[Molecular Weight]

160.17
Chemical PropertiesBack Directory
[Melting point ]

231-233 °C(lit.)
[Boiling point ]

286.07°C (rough estimate)
[density ]

1.1846 (rough estimate)
[refractive index ]

1.5570 (estimate)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO : 50 mg/mL (312.17 mM; Need ultrasonic)|
[form ]

powder to crystal
[pka]

3.60±0.20(Predicted)
[color ]

White to Almost white
[Water Solubility ]

Water : < 0.1 mg/mL (insoluble)
[λmax]

316nm(CH3CN)(lit.)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-37/39
[WGK Germany ]

3
[RTECS ]

VA3677000
[HS Code ]

2933.79.1500
Hazard InformationBack Directory
[Uses]

2-Methyl-4(3H)-quinazolinone may be used in chemical synthesis.
[Synthesis Reference(s)]

Journal of the American Chemical Society, 73, p. 5777, 1951 DOI: 10.1021/ja01156a085
The Journal of Organic Chemistry, 40, p. 144, 1975
[in vivo]

2-Methylquinazolin-4-ol (0.2-1 mg; i.g.; for two days) inhibits ATCase in a dosedependent manner in vivo[2].

Animal Model:Mice[2]
Dosage:0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 1 mg
Administration:Oral gavage, for two days
Result:Showed an inhibitory effect upon ATCase.
Spectrum DetailBack Directory
[Spectrum Detail]

2-METHYL-4(3H)-QUINAZOLINONE(1769-24-0)MS
2-METHYL-4(3H)-QUINAZOLINONE(1769-24-0)1HNMR
2-METHYL-4(3H)-QUINAZOLINONE(1769-24-0)13CNMR
2-METHYL-4(3H)-QUINAZOLINONE(1769-24-0)IR1
2-METHYL-4(3H)-QUINAZOLINONE(1769-24-0)IR2
2-METHYL-4(3H)-QUINAZOLINONE(1769-24-0)Raman
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