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1775330-54-5

1775330-54-5 Structure

1775330-54-5 Structure
IdentificationBack Directory
[Name]

Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl-
[CAS]

1775330-54-5
[Synonyms]

Pyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(1H)-one, 7-[2-[4-bromo-5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]acetyl]-5,6,7,8-tetrahydro-2-phenyl-
[Molecular Formula]

C22H18BrF3N6O2
[MOL File]

1775330-54-5.mol
[Molecular Weight]

535.32
Chemical PropertiesBack Directory
[Boiling point ]

668.5±65.0 °C(Predicted)
[density ]

1.72±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

8.05±0.20(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

PAT1inh-B01 is a selective SLC26A6 inhibitor. PAT1inh-B01 inhibits PAT1 (a Cl-/HCO3- exchanger)-mediated anion exchange (IC50: 350 nM). PAT1inh-B01 blocks fluid absorption in small intestine. PAT1inh-B01 can be used for research of small intestinal hyposecretory disorders[1].
[References]

[1] Cil O, et al. SLC26A6-selective inhibitor identified in a small-molecule screen blocks fluid absorption in small intestine. JCI Insight. 2021 Jun 8;6(11):e147699. DOI:10.1172/jci.insight.147699
1775330-54-5 suppliers list
Company Name: Nantong QuanYi Biotechnology Co., Ltd  
Tel: 0513-66337626 18051384581
Website: https://www.chemhifuture.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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