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178820-70-7

178820-70-7 Structure

178820-70-7 Structure
IdentificationBack Directory
[Name]

AQ 148
[CAS]

178820-70-7
[Synonyms]

AQ 148
(2S)-1-[(S)-benzamido-benzyl-methylazaniumyl]-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutan-2-olate
[Molecular Formula]

C30H37N3O4
[MOL File]

178820-70-7.mol
[Molecular Weight]

503.639
Hazard InformationBack Directory
[Description]

AQ 148 is a potent competitive inhibitor of HIV-1 PR.
[Uses]

AQ148 is a HIV-1 protease inhibitor (Ki=137 nM). The IC50 values ??of AQ148 for the inhibition of HIV-1, HIV-2 and SIV aspartic proteases are 1.5 μM, 3.4 μM and 5 μM, respectively[1].
[References]

[1] Rutenber, et al. "A new class of HIV-1 protease inhibitor: the crystallographic structure, inhibition and chemical synthesis of an aminimide peptide isostere." Bioorganic & medicinal chemistry 4.9 (1996): 1545-1558. DOI:10.1016/0968-0896(96)00147-2
178820-70-7 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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