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179045-86-4

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179045-86-4 Structure

179045-86-4 Structure
IdentificationBack Directory
[Name]

Unii-9927mt646m
[CAS]

179045-86-4
[Synonyms]

Simulect
Bailiximab
SDZ-CHI 621
Unii-9927mt646m
from USAN List 422
Immunoglobulin G 1 (human-mouse monoclonal chi621 heavy chain anti-human interleukin 2 receptor), disulfide with human-mouse monoclonal chi621 light chain, dimer
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Liquid
[color ]

Colorless to light yellow
Safety DataBack Directory
[Hazardous Substances Data]

179045-86-4(Hazardous Substances Data)
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[Uses]

Immunosuppressant (monoclonal antibody).
[Brand name]

Simulect (Novartis).
[in vivo]

Basiliximab (CHI 621) (0.07 mg/rat; i.v.; once) decreases total placental natural killer cells in reduced uterine perfusion pressure (RUPP) rats[2].

Animal Model:Timed-pregnant Sprague Dawley (SD) rats, reduced uterine perfusion pressure (RUPP) rat model of placental ischemia[2]
Dosage:0.07 mg/rat
Administration:IV infusion, once
Result:Decreased total placental natural killer cells. Had no effect to lower MAP or improve pup weight and placental weight.
[storage]

Store at -20°C
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