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179101-49-6

179101-49-6 Structure

179101-49-6 Structure
IdentificationBack Directory
[Name]

5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate)
[CAS]

179101-49-6
[Synonyms]

ap-dUTP
5-PA-dUTP
ap-dUTP·3TEA
5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine
5-(3-Amino-1-propyn-1-yl)-2'-deoxyuridine 5'-triphosphate sodium salt
Uridine 5'-(tetrahydrogen triphosphate),5-(3-amino-1-propynyl)-2'-deoxy-
5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate)
Uridine 5'-(tetrahydrogen triphosphate), 5-(3-amino-1-propyn-1-yl)-2'-deoxy-
[Molecular Formula]

C12H18N3O14P3
[MDL Number]

MFCD28134652
[MOL File]

179101-49-6.mol
[Molecular Weight]

521.2
Chemical PropertiesBack Directory
[density ]

1.95±0.1 g/cm3(Predicted)
[solubility ]

Water
[form ]

Solid
[pka]

0.97±0.50(Predicted)
[color ]

Yellow
[InChIKey]

BGGIMXKBIBMKBL-IVZWLZJFSA-N
[SMILES]

C(OP(=O)(O)OP(O)(=O)OP(O)(O)=O)[C@H]1O[C@@H](N2C=C(C#CCN)C(=O)NC2=O)C[C@@H]1O
Hazard InformationBack Directory
[Description]

5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate), also known as 5-PA-dUTP or 5-Propargylamino-dUTP, is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
[Uses]

5-(3-Amino-1-propyn-1-yl)-2''-deoxyuridine 5''-(Tetrahydrogen Triphosphate) is an intermediate in the synthesis of Texas Red-5-dUTP (T320100), a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma.
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