| Identification | Back Directory | [Name]
(R)-Gyramide A Hydrochloride | [CAS]
1793050-70-0 | [Synonyms]
(R)-Gyramide A Hydrochloride
5-fluoro-2-methyl-N-[(3R)-1-[[4-(1-methylethoxy)phenyl]methyl]-3-pyrrolidinyl]-benzenesulfonamide, monohydrochloride | [Molecular Formula]
C21H28ClFN2O3S | [MOL File]
1793050-70-0.mol | [Molecular Weight]
442.97 |
| Hazard Information | Back Directory | [Uses]
(R)-Gyramide A Hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity. It does not affect the closely related enzyme topoisomerase IV. | [Uses]
(R)-Gyramide A is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 μM. It does not affect the closely related enzyme topoisomerase IV. (R)-Gyramide A demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs range from 10-80 μM).[Cayman Chemical] |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Lynnchem
|
| Tel: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Website: |
https://www.novachemistry.com/ |
|