ChemicalBook--->CAS DataBase List--->179386-43-7

179386-43-7

179386-43-7 Structure

179386-43-7 Structure
IdentificationBack Directory
[Name]

Sumanirole maleate
[CAS]

179386-43-7
[Synonyms]

Sumanirole
(5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one
4H-IMidazo[4,5,1-ij]quinolin-2(1H)-one,5,6-dihydro-5-(MethylaMino)-, (5R)-
(R)-5-(MethylaMino)-5,6-dihydro-1H-iMidazo[4,5,1-ij]quinolin-2(4H)-one Maleate,(free base)
(5R)-5,6-Dihydro-5-(MethylaMino)-4H-iMidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-Butenedioate
(R)-5,6-Dihydro-5-(MethylaMino)-4H-iMidazo[4,5,1-ij]quinolin- 2(1H)-one (2Z)-2-Butenedioate
[Molecular Formula]

C11H13N3O
[MOL File]

179386-43-7.mol
[Molecular Weight]

203.24
Chemical PropertiesBack Directory
[density ]

1.32
[storage temp. ]

2-8°C(protect from light)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P280-P305+P351+P338
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Light Beige Solid
[Uses]

Sumanirole is a high affinity D2 receptor agonist (EC50 values are between 17 and 75 nM in cell-based assays). Sumanirole displays >200-fold selectivity for the D2 receptor against other dopamine rece ptor subtypes (Ki values are 9.0, 1940, >2190 and >7140 for D2, D3, D4 and D1 receptors respectively). Sumanirole exhibits antiParkinsonian activity similar to Ropinirole (R641000).
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