| Identification | Back Directory | [Name]
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide | [CAS]
179420-17-8 | [Synonyms]
CJ-13610
CJ-13610
(CJ13610)
CJ-13610 >=98% (HPLC)
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide
2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-
4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610 | [Molecular Formula]
C22H23N3O2S | [MDL Number]
MFCD00948114 | [MOL File]
179420-17-8.mol | [Molecular Weight]
393.5 |
| Chemical Properties | Back Directory | [Melting point ]
208-210 °C | [Boiling point ]
681.0±65.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥10mg/mL | [form ]
powder | [pka]
15.77±0.20(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling. | [Biochem/physiol Actions]
CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the IL-6 mRNA expression in macrophages. It reduces fibrosis and necroinflammation of liver in carbon tetrachloride-treated mice. | [storage]
Store at -20°C |
|
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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