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1796933-62-4

1796933-62-4 Structure

1796933-62-4 Structure
IdentificationBack Directory
[Name]

2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline
[CAS]

1796933-62-4
[Synonyms]

Palonosetron Impurity 51
2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline
1H-Benz[de]isoquinoline, 2-(3R)-1-azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-, (3aR)-rel-
[Molecular Formula]

C19H26N2
[MOL File]

1796933-62-4.mol
[Molecular Weight]

282.42
Chemical PropertiesBack Directory
[Boiling point ]

411.7±40.0 °C(Predicted)
[density ]

1.16±0.1 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

Methanol
[form ]

Solid
[pka]

10.56±0.33(Predicted)
[color ]

Yellow
Hazard InformationBack Directory
[Uses]

2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline is an intermediate in the sythesis of (S,S)-Palonosetron Acid which is an impurity in the synthesis of (S,S) Palonosetron (P165800), serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
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