| Identification | Back Directory | [Name]
4(1H)-Quinolinone, 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]- | [CAS]
1801444-56-3 | [Synonyms]
RYL-552
4(1H)-Quinolinone, 5-fluoro-3-methyl-2-[4-[[4-(trifluoromethoxy)phenyl]methyl]phenyl]- | [Molecular Formula]
C24H17F4NO2 | [MOL File]
1801444-56-3.mol | [Molecular Weight]
427.39 |
| Chemical Properties | Back Directory | [Boiling point ]
496.3±45.0 °C(Predicted) | [density ]
1.309±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
0.77±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor[1]. | [Biological Activity]
RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor[1]. | [storage]
Store at -20°C | [References]
[1]. Kristin D Lane, et al. Selection of Plasmodium falciparum cytochrome B mutants by putative PfNDH2 inhibitors. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6285-6290. |
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