1802499-21-3

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1802499-21-3 Structure

Chemical Properties	Back Directory
[density ] 1.220±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 8.683±0.43(predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] TAM558 is a payload molecule used for the synthesis of OMTX705. OMTX705 is a humanized anti-fibroblast-activating protein (FAP) antibody conjugated to the cytolysin TAM470.html" class="link-product" target="_blank">TAM470 (HY-148128), with antitumor activity[1].
[References] [1] Fabre M, et al. OMTX705, a Novel FAP-Targeting ADC Demonstrates Activity in Chemotherapy and Pembrolizumab-Resistant Solid Tumor Models. Clin Cancer Res. 2020 Jul 1;26(13):3420-3430. DOI:10.1158/1078-0432.CCR-19-2238

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