| Identification | Back Directory | [Name]
3'-beta-C-Ethynyladenosine | [CAS]
180300-54-3 | [Synonyms]
3'-?C-Ethynyladenosine
3’-β-C-Ethynyladenosine
Adenosine, 3'-C-ethynyl-
3'-beta-C-Ethynyladenosine | [Molecular Formula]
C12H13N5O4 | [MOL File]
180300-54-3.mol | [Molecular Weight]
291.26 |
| Hazard Information | Back Directory | [Uses]
3’-β-C-Ethynyladenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. 3’-β-C-Ethynyladenosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020 |
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