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1804910-11-9

1804910-11-9 Structure

1804910-11-9 Structure
IdentificationBack Directory
[Name]

Research Grade Valziflocept
[CAS]

1804910-11-9
[Synonyms]

Research Grade Valziflocept
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Colorless to light yellow
Hazard InformationBack Directory
[Uses]

Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor that targets Fc and FcγR. FcγRs bind and neutralize pathogenic IgG, thus forming a "decoy" or "scavenger" receptor that can reduce the severity of autoimmune diseases. Valziflocept can be used in studies of autoimmune diseases such as systemic lupus erythematosus (SLE)[1].
[References]

[1] Adrian W Zuercher, et al. Next-generation Fc receptor-targeting biologics for autoimmune diseases. Autoimmun Rev. 2019 Oct;18(10):102366. DOI:10.1016/j.autrev.2019.102366
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