| Identification | Back Directory | [Name]
Benzyl-PEG5-CH2CO2tBu | [CAS]
1807503-89-4 | [Synonyms]
BnO-PEG4-Boc
Benzyl-PEG5-CH2CO2tBu
3,6,9,12,15-Pentaoxahexadecanoic acid, 16-phenyl-, 1,1-dimethylethyl ester | [Molecular Formula]
C21H34O7 | [MDL Number]
MFCD28122960 | [MOL File]
1807503-89-4.mol | [Molecular Weight]
398.49 |
| Hazard Information | Back Directory | [Description]
Benzyl-PEG5-CH2CO2tBu is a PEG linker with a benzyl and t-butyl protecting group. Both protecting groups are acid labile. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media. | [Uses]
BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|