1807503-89-4

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1807503-89-4 Structure

Identification	Back Directory
[Name] Benzyl-PEG5-CH2CO2tBu
[CAS] 1807503-89-4
[Synonyms] BnO-PEG4-Boc Benzyl-PEG5-CH2CO2tBu 3,6,9,12,15-Pentaoxahexadecanoic acid, 16-phenyl-, 1,1-dimethylethyl ester
[Molecular Formula] C21H34O7
[MDL Number] MFCD28122960
[MOL File] 1807503-89-4.mol
[Molecular Weight] 398.49

Chemical Properties	Back Directory
[solubility ] Soluble in DCM, DMF
[form ] Liquid
[color ] Colorless to light yellow

Hazard Information	Back Directory
[Description] Benzyl-PEG5-CH2CO2tBu is a PEG linker with a benzyl and t-butyl protecting group. Both protecting groups are acid labile. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.
[Uses] BnO-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Spectrum Detail	Back Directory
[Spectrum Detail] Benzyl-PEG5-CH2CO2tBu(1807503-89-4)¹HNMR

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